I have created this chart to visually represent the universal role Bisantrene plays in cardioprotection against common cardiotoxic chemotherapies. A 1 uM dose of Bisantrene significantly improves HCM viability (p < 0.001). The real value for this opportunity is that while providing cardioprotection, Bisantrene improves cancer cell killing in combination with these chemotherapies. There are already 2 clinical trials where Bisantrene is used in combination with moderately cardiotoxic chemotherapies not listed in the figure below that achieved combined ORR of 46% and 40% with no clinically relevant signs of cardiotoxicity.
A drug with a universal cardioprotection mechanism combined with a universal cytotoxicity mechanism has not existed until now.
I have created this chart to visually represent the universal...
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Last
$1.57 |
Change
-0.035(2.18%) |
Mkt cap ! $266.3M | |||
| Open | High | Low | Value | Volume |
| $1.59 | $1.62 | $1.56 | $101.6K | 64.09K |
Buyers (Bids)
| No. | Vol. | Price($) |
|---|---|---|
| 2 | 7451 | $1.55 |
Sellers (Offers)
| Price($) | Vol. | No. |
|---|---|---|
| $1.60 | 408 | 1 |
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| Last trade - 15.53pm 05/06/2024 (20 minute delay) ? |
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Last
$1.58 |
Change
-0.035 ( 1.25 %) |
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| Open | High | Low | Volume | ||
| $1.58 | $1.62 | $1.56 | 7255 | ||
| Last updated 15.57pm 05/06/2024 ? | |||||
| RAC (ASX) Chart |