From memorial Sloan Kettering in NY
The immunotype that jumped out was a group of patients who had high levels of a protein called LAG-3 expressed on various T cell subsets. Patients with this LAG+ immunotype, the team found, had a much shorter survival time compared with patients with a LAG- immunotype: For melanoma patients, there was a difference in median survival of more than four years (22.2 months compared with 75.8 months) and the difference was statisticallysignificant
To me the more confirmation the more confident I become. The part that jumps out to me, is where she talks about not looking particularly at lag-3 but following the data led them to this discovery.
https://www.sciencedaily.com/releases/2021/08/210825153747.htm
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Memorial Sloan Kettering Validation of LAG-3 impact
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