Background on M1/M2 good in this article (which is concerned with redox basis for M1/M2 switch).
"Macrophage polarization refers to the process by which macrophages produce distinct functional phenotypes as a reaction to specific microenvironmental signals. It is considered that macrophages can polarize in two distinct subsets: M1 or M2 macrophages."
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311967/
MSB Science, page-3
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