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PAR 1.96% 26.0¢

PARADIGM BIOPHARMACEUTICALS LIMITED..

Paradigm Biopharmaceuticals Limited is a late-stage drug development company. It is... Paradigm Biopharmaceuticals Limited is a late-stage drug development company. It is engaged in researching and developing therapeutic products for human use. It is focused on the development of injectable pentosan polysulfate sodium (iPPS/PPS) for the treatment of osteoarthritis (OA). Pentosan polysulfate sodium is a semi-synthetic drug manufactured from the wood chips of European beech trees. Extracted glucurono-xylans are sulfated to produce a negatively charged product that mimics glycosaminoglycans (GAGs). It develops PPS under the brand name Zilosul. PPS clears cellular and tissue accumulation of GAGs. PPS also inhibits the synthesis of the metalloproteinase, MMP-3 (Troeberg) involved in degrading cartilage. PPS also include treatment of joint function, mobility, and pain in patients with mucopolysaccharidoses (MPS); treating alphavirus-induced arthralgia (such as Ross River virus and Chikungunya); chronic heart failure (HF) and acute respiratory distress syndrome (ARDS).More

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Timeline

Change in substantial holding
22 May 08:24
 
Application for quotation of securities - PAR
20 May 16:03
 
Quarterly Activities/Appendix 4C Cash Flow Report
30 Apr 09:54
 
Notification of cessation of securities - PAR
26 Apr 16:46
 
Type D Response Submitted and Received by the US FDA
19 Apr 08:36
 
Notification of cessation of securities - PAR
05 Apr 19:49
 
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26.0¢
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Mkt cap ! $90.94M
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26.5¢ 26.5¢ 25.5¢ $68.79K 263.0K

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Last trade - 14.52pm 27/05/2024 (20 minute delay) ?
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