NEU 0.18% $19.27 neuren pharmaceuticals limited

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  1. 16,337 Posts.
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    me to , love Neu if it gets to 10c .

    from presentation in 2011 for those who are Neu

    Market potential on NNZ-2566

    1.5 million brain injuries per year in the US alone

    No approved therapies

    Assuming $12,000 for IV and $3,000 for oral as price point, total potential market value is:

    Moderate –severe = ~$2 billion

    Mild = ~$2 billion

    ~$500 million peak annual sales forecast (15% market penetration; hospitalized and emergency department patients only)
    Competitive advantages

    Only product to address the full range of TBI from mild to severe

    Only competitive product currently in Phase II or beyond is progesterone

    Two approvable outcomes: neurological function andprevention of seizures

    Mechanism reflects broad pharmacologic actions of a naturally occurring product

    Excellent safety profile: few serious adverse events and no known or expected drug interactions

    Key opinion leaders (KOLs) already involved and committed
    Partnership opportunities

    US Army financing development; will be a major client (no residual rights)

    Partnership opportunities in multiple fields and indications for oral and intravenous



    Intravenous administration

    TBI (moderate to severe)*
    Stroke
    Cardiac arrest
    Perinatalasphyxia
    Penetrating brain injury
    Non-convulsive seizures in other CNS injuries/conditions

    Oral administration

    Mild TBI*
    RettSyndrome/other autism spectrum disorders*
    Post-stroke recovery
    Prophylaxis following transient ischemic attack
    Chemotherapy-induced neuropathy



    Market potential of Motiva

    Market potential for apathy in selected indications
    16
    Stroke: $1,248,000,0001
    Traumatic brain injury: $840,000,000
    Parkinson’s disease: $1,056,000,000
    1 Assumes reimbursement at $2,400 per year
    Peak annual sales forecast2(10% market penetration): ~$280 million


    RettSyndrome

    Largest single cause of intellectual disability and autism in females;
    genetic disorder caused by a mutation in the MECP2gene

    Normal infant development followed by loss of language, social contact
    and motor functions, epilepsy

    Large market potential –US = $430 million; global = $1.2 billion

    http://www.stocknessmonster.com/news-item?S=NEU&E=ASX&N=641987

    http://ausbiotech2011.com.au/uploads/Neuren.pdf


 
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