Ann: Sirtex Completes SIRFLOX Patient Recruitment, page-6

re: Ann: Sirtex Completes SIRFLOX Patient Rec... The study concerns FOLFOX and SRX as 1st line treatment.

Even FOLFOX is being overtaken by the newer biomedics drugs.

FOLFOX is a chemotherapy regimen for treatment of colorectal cancer, made up of the drugs

FOL– Folinic acid (leucovorin)
F – Fluorouracil (5-FU)
OX – Oxaliplatin (Eloxatin)[1]


About the SIRFLOX study

The SIRFLOX study is an international research study designed to evaluate a new treatment option for patients with colorectal cancer that has undergone metastatic spread to the liver. The study is designed to evaluate whether FOLFOX chemotherapy in combination with Selective Internal Radiation Therapy is more effective than chemotherapy alone. This study represents the first time that these treatments have been assessed together as part of a randomised controlled study and as a first-line therapy (i.e. in patients who have not previously received chemotherapy for their liver metastases).