nanoparticles trigger tumor cells to destruct, page-5

Apologies in advance jtraynor!

Interesting article

"The nanoparticles contain a surface marker that directs them to attach to the cell’s lysosomes."

There is a link that takes you to the original abstract (in blue below)

To this end, we covalently conjugated superparamagnetic iron oxide nanoparticles (SPIONs) with antibodies targeting the lysosomal protein marker

So it is basically getting a protein to stick to an iron ore particle, that is this ?ingested, ?injected into the blood stream and in turn is attracted to a protein associated with the cancer.

Then the magnetic field is used to rotate the nanoparticle which rips the cancer cell apart.

Sticking to a nanoparticle, I wonder what could help?


AMG™ Universal Binding Kits
One step protein coupling onto magnetic particles

---------------------------------------------

Hassle Free Conjugation

In as little as one step you can successfully bind
your protein of interest to either 200 nm or 1 µm
magnetic beads using the AMG Universal Binding
Kit. Coating Mix&Go pre-activated, ready-to-use
particles with proteins (as illustrated above) is a
fast, easy and user-friendly procedure that will let
you get on with the research that matters.

The elimination of activation steps and pretreatment
of proteins allows users to design and
generate novel and complex bead conjugates by
incorporating more than one protein in the
coupling reaction. Anteo scientists have created a
range of co-coupled magnetic beads including a
conjugate containing an enzyme and an antibody
as shown below.

-----------------------------------------

These kits might speed up the research, but what would I know, just being a filby