I have a question regarding the March 2014 presentation slide 12 or 13.
Phase II: 12 Weeks Improvement in Median PFS Is
Encouraging.
Progression Free Survival (PFS) of 5.2 vs. 2.4 months (p=0.017)
Hazard ratio for PFS of 0.56 (p=0.019)
Longer Time to Treatment Failure (4.0 months vs.
1.8 months) (p=0.007)
HA-Irinotecan patients treated for significantly
more cycles (six vs. two) (p=0.005)
No significant increase in toxicity was observed
I am ok with the above, but I am concerned about the p value of the two below.
Increase in DCR (76% vs. 46%, p=0.053)
Trend towards increased overall survival (10.1 vs. 8
months) (p=0.196)
Comments anyone?
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