OMG!
Fail!
When used as a bioprosthetic heart valve, bovine pericardium has been reported to
show mechanical disruption of leaflets and mineralization resulting in early failure
in some cases.
Glutaraldehyde-treated bovine pericardium may undergo accelerated calcific
infiltration in patients with high calcium metabolic activity (e.g., children). This
may not be a concern where the patch is exposed to systolic pressures.
Obviously I hope this won't happen to Cardiocel.
Valve repair study, page-14
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