I think people should read up the difference between clinically significant which is what doctors look at and compare that to statistically significant. Also numbers needed to treat is weirdly not published . I personally found that odd.
An important idea to grasp is that if a study is very large, its result may be statistically significant (unlikely to be due to chance), and yet the deviation from the null hypothesis may be too small to be of any clinical interest. Conversely, the result may not be statistically significant because the study was so small (or "under powered"), but the difference is large and would seem potentially important from a clinical point of view. You will then be wise to do another, perhaps larger, study.
Perhaps looking at the real results would actually give a fair assessment on whether it's an appropriate investment
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- Ann: Preliminary SIRFLOX Study Results
Ann: Preliminary SIRFLOX Study Results, page-49
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