Smallpox vaccination doesn't work, never worked. All Jenner's local colleagues knew that, and told him so. He was only able to propagate his fraud because people in London weren't familiar with cowpox. He called it "smallpox of the cow", variolae vaccinae, and they swallowed that hook, line and sinker. He said it was a milder form of smallpox, so it was better to inoculate with smallpox of the cow, rather than with smallpox itself (a very common practice at the time).
So it isn't a question of an alternative to vaccination at all.
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