Going back to neutral's original post, may I throw some dates and supposition out there.
The TBI trial is due to finish January so I would guess report to market in March-April, should be in time for the AGM.
The concussion trial is listed as finishing in June, so let's say it gets reported to market in September. Neuren haven't put out an ann on this for a while, so that one's subject to revision, you'd guess end of 2016 should be a worst case there.
Given previous experience and timelines, Neuren may put the FXS results up for Breakthrough, and if they do it will be on the quiet. Given the Rett experience, if BT happens it will be announced in March.
The next Rett trial should be announced soon - I would hope by end year- and should recruit soon too, say starting this by March
Given the trajectory seems to be the same for FXS ans Rett (IIb then III) I wonder how much NEU can leverage from the Rett experience to speed up the FXS process. To put things in perspective, it's a year since the Rett results and the next trial hasn't started yet. The other question is what process will be required (and how long will it take) to get to market in the TBI sphere. The Ph II trial in TBI took 9 years. The mild TBI trial will take about 2, so that's been quicker, but remember they took about 2 years just to get the ball rolling because the paperwork took so long.
Otherwise:
2016 Rett IIb, concussion and TBI announced.
2017 Rett III, FXS IIb
2018 Rett submission paperwork, FXS III
2019 Rett out to market
2020 FXS out to market
At a guess mild TBI out to market by 2020
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