Here is one of the reasons I think drugs like Coramsine will be so valuable with the new cancer vaccines.
"The Provenge trial protocol in asymptomatic AIPC allowed enrollment of men with bone mets, but not with visceral mets. The distribution of memory T cells throughout the body thereafter could block the initial establishment of those slow growing visceral mets that kill AIPC patients. (9) Studies with other cancer vaccines have shown that post vaccination chemo killed memory T cells along with regulatory T cells reducing or eliminating their efficacy, Provenge's Fisher Exact p values for ITT patients subsequently treated with chemo supports that hypothesis. "
Found that on invstorvillage.
http://www1.investorvillage.com/smbd.asp?mb=971&mn=3307&pt=msg&mid=345828
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