YES we can: eg the founding asset/mine of one of the greatest now gold company in OZ - Northern Star - NST, have started from one "depleted" Paulsens mine discarded by others and grew to $2.5 bln company picking up assets others give up and making money, paying dividends, growing resources...
Paulsens mine never have and still does not have much reserves, as it is expensive business drilling and "proving" but it is still working and producing: http://www.nsrltd.com/wp-content/uploads/2017/02/BMO-Presentation-27-2-2017.pdf
It has only 100K oz reserve but is working and producing without much reserve since 1930s: https://en.wikipedia.org/wiki/Paulsens_Gold_Mine
If you can expect more gold to find there is no better place than around Kalgoorlie' Super Pit and the last but not least - MRP has 2 assets which may be of interest to others too!
MRP Price at posting:
24.5¢ Sentiment: Buy Disclosure: Held