Am no microbiologist but I've always wondered why they (i.e. analysts, the illuminati, etc) continue to compare vax reductions in viral sheddings vs antivirals? Taking antivirals means taking them everyday for life... that's say maybe 1-2 tubes of zovirax a month at $15-30 per month, $150-300 per year, $1,500-3,000 for every ten years. Then you have the compliance issue, which I'd say 100% of the HSV population would be non-compliant at multiple points over the life of taking antivirals (beyond the life of a clinical trial), and then there's the risk of viral resistance and/or the non-compliance forcing a viral mutation. My point is they should focus on Genocea results as the benchmark to beat and not worry too much about antiviral reductions.... viral shedding reductions and convenience/compliance/cost combination means reductions dont need to beat 70-80% IMO...
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