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Ann: Appendix 4E, page-174

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  1. 1,868 Posts.
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    How is the ETP (Milestone 2) triggered by Wave II? Can someone help me out here, but my understanding was that Wave II (the Magnetic Booster) does not involve ETP technology at all.

    "ETP is a nonpowered active magnetic materials technology that uses micro-arrays of magnetic gradients which mobilize drug molecules and alter the barrier effect through a combination of Diamagentic repulsion and Induce Charge electro Osmosis. The ETP material contains complex intersecting polarity magnetic arrays in a flexible polymer matrix that generate a multiphasic magnetic field capable of enhancing transdermal delivery without disrupting the skin barrier function. It achieves this by utilising diamagnetic repulsion to give energy and directionality during partitioning and diffusion and induced charge electro-osmosis as a means of optimizing delivery pathways. (see Mechanisms of Action, section 5) ETP can be readily incorporated as the patch backing layer in existing drug-in-adhesive and matrix patch technologies to provide a cost-effective and continuous “active patch” delivery solution."

    http://www.obj.com.au/images/documents/ETP-eM-patch-Summary-Results.pdf
 
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