Ann: Appendix 3Y - Change of Director's Interest Notice x 2, page-17

Not to mention the holders still patiently waiting. Seeing the directors committment is clearly a good indicator that their confidence is still high despite the disappointing NAD001 result. The posts of the doomsayers are exactly what we should have expected. They will run their hands together on any negative news but they have been conspicuous by their absence in the past when the share price rose and they will scurry off again as soon as any good news comes out- and it will. Go NAG be patient guys hold the line.