BIT 5.00% 1.9¢ biotron limited

updates about the deals, page-44

  1. 19,318 Posts.
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    As far as I can find in what BIT has released they have not shown that they can clear HIV from macrophages, just target HIV in macrophages when tested in cell culture (at ~10x the concentration of BIT225 they likely reached in the latest trial).

    BIT225 targets HIV in macrophages in the same way that cART targets HIV in T-cells. BIT as far as I can find have no evidence that BIT225 is able to target latent HIV integrated into the DNA of macrophages. Given the mechanism of action of BIT225 (targeting the late expressed HIV protein VPU) this is not surprising.

    If you read what MM has said you will see she is careful to never say that BIT225 is able to target latent HIV in macrophages.
 
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