Ann: Appendix 4C - quarterly, page-20

for those who do not find a plausible motivation for today's price per share fall, I suggest taking seriously the important and difficult issue Neuren is facing in order to perfect the US patent for 2591. It is a few hours ago, last invitation to the company by the commission to clarify precisely how and what it is intended to change formally to the patent in question. last term available two months and no later to do so.whether it is considered important or not, this is a fundamental element in determining the value of Neuren's intellectual property and given that in these months we are talking about an important agreement, those who put their money into it will certainly have the need to have the certainty of the facts and contents on which to invest.from my point of view, this is fundamental for the market by virtue of a bet in the short term; delays and uncertainties justify, rightly or wrongly, those who have decided today to divest and retire to the window and wait for certain elements.there will be no announcements of important agreements without the clear determination of Neuren's intellectual value and I will also put the official status of the European patent still to be received.