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    Thanks W7s.

    @RaceOncology

    If we take it as given that Bisatrene works as a single agent, is there not a significant risk that it does not work when combined with other agents in trials. Due to: high cancer burden (late stage, ie not being used as a front line treatment), weakened immune system of late stage patients/chemo, unknown interactions.

    Getting the best drugs to the front line seems to be an industry elephant in the room from patients point of view. Understandably difficult for ethical reasons of course, and not even broaching market power and commercial interests etc.

    How we can evaluate the weight of this risk here?

    Cheers. (apologies if this is already a well covered subject)

 
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