But I am speaking about the science with regards to the tests used -
The test used is a behavioral test, whereas neuroscience has many better investigation techniques that have been standard for the last 25 years:
For example, the effects of Xanamem on long term potentiation (LTP) in the hippocampus would be the standard test for investigation of a new drug compound and its action(s) on cellular memory - this work seems to be missing.
Occupancy studies & binding to 11-beta-HSD-1 cortisol-activation enzyme have no direct link to memory.
I am hoping for some sophisticated science to put a link between Xanamem treatment and its impact on memory beyond the cited behavioural tests : )
11βHSD1 inhibitor use in human disease- a systematic review and narrative synthesis, page-62
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