Just flicking through some news articles and this provided some interest with relevance to gut cancers, immunotherapy and gut biome effect.
"Research revealed that specific bacteria were essential to the immunotherapy working. The tumours shrank, drastically. For those subjects that did not receive the beneficial bacteria, the immunotherapy had no effect." Working on mouse models at present but starting on human trials in future.
https://www.news-medical.net/amp/news/20200813/Researchers-discover-how-gut-bacteria-help-the-immune-system-to-battle-cancerous-tumors.aspx
Imugene - Fundamentals, page-171
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