Hopefully preparing for another attack on 1.80 level shortly.at least we still have plenty of time before any results spoil the party. Theory says phase 1 should be ok. Look at TIS for what happens when you fail, at phase 2 believe it or not. I guess that is the danger here, we could sail thro phase 1 as only healthy subjects used. That being said surely one would assume they have done multiple trials with animals with actual infection to see how the body copes with bacteria die off.
Ann: R327 Phase I Study - Australia's CMAX Clinical Facility, page-38
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