The second is BTM as the subject of an abstract which was presented a few weeks ago at a conference of the Ohio Valley Society of Plastic Surgeons. The authors are surgeons at Metro Health Medical Centre in Cleveland, Ohio.
It was David Williams, I think, who mentioned recently that PolyNovo aims to have BTM used by the best doctors, in the best hospitals. Metro Health certainly fits the bill, having been named by USNews as No. 2 hospital in the United States for 2020/2021.
The abstract is titled
Comparison of Biodegradable Temporizing Matrix and Collagen-Chondroitin Silicone Bilayer Dermal Regeneration Substitutes
To be clear, Integra Dermal Regeneration Template is a collagen bi-layer made of bovine type I collagen and shark chondroitin-6-sulphate GAG that is bonded to a silicone pseudo-epidermis.
On other words, in this Metro Health study, Novosorb BTM was compared with Integra Dermal Regeneration Template.
The retrospective study analysed adult patients who underwent wound reconstruction with either BTM or Integra from 2015 through to mid-2020. Types of wounds included burn, trauma, surgical wounds, osteomyelitis, and compartment syndrome.
97 patients were included in the study - 51 were treated with BTM and 46 were treated with Integra.
Skin graft failure was found to be higher in the Integra group at 9 (23.1%) compared to 1 (3.6%) in the BTM group (p=0.006). Median template size was 147 cm2 for BTM and 100 cm2 for Integra. Skin grafts were applied after template in 39 (84.8%) of the Integra cases compared to 28 (54.9%) in the BTM group (p=0.006), with the remainder of wounds healing secondarily.
More secondary procedures were needed in the Integra group. Final closure was achieved in a similar percentage of cases (~60%). Mean time to closure was said to be 5.4ą3.8 months after BTM and 6.4ą8.9 months after Integra placement (p=0.591).
The authors concluded that BTM has comparable complication rates and outcomes with fewer secondary procedures and skin grafts needed. In what is surely a typo, the authors cited a cost of US$850 per 100 cm2 for BTM, compared to US $20,325 for Integra, and concluded that BTM could be considered an economical option for wound reconstruction.
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