The controls for the aGVHD trial were not satisfactory and were fudged by SI. MSB even told investors before the submission that they were working on providing a "control group" for the FDA but that they "may not find it acceptable". They didn't. Perhaps you missed the warnings and then didn't understand why the FDA rejected the trial results. Go back and have a look.
The most important "tick tock " is the time to MSB funds running down to the point they aren't sufficient to satisfy the loan covenants.
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