started out ok.... basic and concise summary....
- "normal" vaccines were attenuated, or weakened, live virus. this is what caused many in the 70's-2000's who had the flu vax to get sick with the flu. it caused active immunisation but was often too strong for many and so they got sick, even in my peak immune system age of 20-40 yrs when I had the attenuated virus vaccine I got sick.
- the mRNA vaccines contain a small piece of the vaccine RNA, which uses messenger (m) RNA to transfer the virus' RNA to the nucleus and blocks the reproduction of the virus. it also contains the spike protein on the virus enables it the unlock the host cell and let it be absorbed into the host cell.... its the key also to the immune system identifying the virus. The vaccine using the protein spike causes the immune system to prepare antigens which can identify the virus (memory T and B cells) and direct the antigens to attack the virus.
- so the mRNA vaccines work in two ways to defeat the virus and prevent reproduction of the virus.
- this means that a vaccinated person is highly unlikely to achieve a viral load that can infect others. caveat: dependent on the hosts ability to produce antigens.
- far from being crude, the technology was developed in the early 2000's as a response to SARS. its is a highly sophisticated technology that few nations yet possess, hence requests from poor nations for Pfizer and Moderna to release the patent and allow poor nations to develop their own version of mRNA.
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7827936/
- AstraZeneca vaccine is different. it contains attenuated common cold virus produced through a different method which ensures the virus will not cause illness.
- because it uses attenuated virus, it can trigger a covid-like response which includes cytokine storm (an immune response) which then may cause minor clotting, Thrombosis with Thrombocytopenia Syndrome, distinctly unlike the severe cytokine storm of the live infection but using the same means of action.
- the DNA of the virus is inserted into an adenovirus (weakened) and so the virus is able to enter the host cells with the DNA instruction to produce the spike protein from which the immune system can learn to identify the virus.
- the spike protein itself is entirely harmless. it might attach to an ACE2 but it has no virus with which to allow entry into the host cell. most proteins just float around the blood stream till all are gobbled up by macrophages (essentially the vacuum cleaners of the body produced by the immune system)
- https://www.health.gov.au/sites/default/files/documents/2021/04/covid-19-vaccination-information-on-covid-19-astrazeneca-vaccine_0.pdf
I could go into more and deeper detail but I don't want this post to be so long none will read it.
the links are easily read and understood but if you want more technical information, I suggest you. write to AZ, TGA or the other companies.
Why do we need booster jabs? Just like with tetanus, the immune response has a limited life span. the antigens initially produced cease to develop and mature in the absence of live virus exposure, however the memory cells don't diminish. this doesn't mean there is no immune response but that antigens must be produced again after around 3-6 months. health authorities want people to have an active immune response immediately on exposure so they want booster jabs to ensure the antigen level is high.
I hope this helps Geno
mate, I've had decades of being corrected because I didn't know much when I was younger..... I learned to research info. I'm not a smart bugger, or a smart arrrs.... but I learned to always be prepared to have my beliefs challenged and to learn new information from authorities who do actually know what they're talking/writing about.
don't trust my words....., dyor and gl ;-)
