Interesting to see who else is in "the race"
In my mind, it doesn't really matter who is past the post first.
The fact that each company will learn from each other's success or failure, will no doubt lead to a better outcome for the millions of people suffering from mental health conditions word-wide.
If you are interested in learning more about this space this is an interesting website to browse.
https://psilocybinalpha.com/data/psychedelic-drug-development-tracker
Another interesting thought moving forward for IHL is where will we conduct future trials outside of Australia because we are so blessed here in AUS with fairly liberal laws to conduct research using restricted substances. It's not so straightforward in the USA.
View this page to see an interactive map >>> https://psilocybinalpha.com/data/psychedelic-laws
Some planning may be needed to select what locations - future stages & trials for OSA - will be conducted (assuming that we do move some to the USA) to take into account each US States drug law in respect to research involving dronabinol.Interesting article concerning "Marinol"
What's the Difference Between Marinol and Medical Marijuana?ByKellie Pantekoek, Esq.| Reviewed byBridget Molitor, J.D.| Last updated April 21, 2020
Marinol is a prescription drug containing the active ingredient dronabinol, a synthetic form of tetrahydrocannabinol (THC). THC is the main psychoactive (brain altering) ingredient in marijuana. It is responsible for the "high" some users seek. However, THC also has powerful medicinal capabilities, which is why scientists created Marinol decades ago as a legal alternative to cannabis in the United States.
Where Is Marinol Legal?
The U.S. Food and Drug Administration approved Marinol for medical uses in 1985. Since then, the drug has been legal in all 50 states. Because it is a regulated pharmaceutical drug, you need a prescription to purchase and use Marinol.
It is against the law to sell or give Marinol away, or to use the drug without a prescription. The improper possession or distribution of prescription drugs can result in criminal charges and the need for a criminal defense lawyer.
How Is Marinol Used?
Marinol and generic dronabinol are approved by the FDA to treat nausea and vomiting caused by cancer chemotherapy, as well as weight loss-related anorexia and loss of appetite in AIDS patients. Off-label and clinical trial uses for Marinol include treatment for:
- Fibromyalgia pain
- Glaucoma-related eye pressure
- Menstrual migraines
- Postoperative nausea and vomiting
- Obstructive sleep apnea
- Muscle spasticity related to multiple sclerosis (MS)
- Neuropathic chronic pain
Because Marinol contains the psychoactive ingredient THC, it can cause serious side effects, including psychosis, especially in people who have a history of mental illness, as well as blood pressure issues. Talk to a doctor immediately about any adverse effects while taking Marinol.
The Differences Between Marijuana and Marinol
There are many differences between the natural plant marijuana (cannabis) and the synthetic cannabinoid Marinol. Legally speaking, the biggest difference is that marijuana is illegal — even for medicinal uses — under federal law, while Marinol can be prescribed legally in any state.
Marinol is a Schedule III drug, which means the government has determined that it has a moderate-to-low risk for dependency. The government still considers marijuana a Schedule I drug, meaning it is not currently accepted for medical use and carries a high risk of abuse.
Beyond the law, other differences include:
- THC occurs naturally in marijuana, while it is chemically engineered in Marinol
- Medical marijuana can be smoked, inhaled as a mist, eaten, applied to the skin, or placed under the tongue. Marinol can only be taken in pill form
- Marijuana has many cannabinoids in addition to THC, while Marinol only contains THC
- Medical marijuana has a faster absorption rate than Marinol, but Marinol remains in the blood for longer than marijuana
- A 2013 study suggested that taking THC in pill form could be more effective at pain relief than smoking THC
- Marinol and generic dronabinol are generally believed to have more intense side effects than natural cannabis
Making a Choice Between Marinol and Marijuana
Individuals who have a medical need and live in a state that has approved medical cannabis should weigh the potential benefits and drawbacks of both medical marijuana and Marinol to determine which option is right for them. Of course, seek medical advice before starting or stopping any medication, including cannabis.
It's important to note that Marinol and generic dronabinol should not be used by anyone other than the patient for whom they were prescribed.
https://www.findlaw.com/cannabis-law/cannabis-laws-and-regulations/what-s-the-difference-between-marinol-and-medical-marijuana-.html
It will be interesting to view some future IHL announcements and any proposed future trials for OSA Phase 2 or Phase 3 (if any are proposed to be conducted in the USA) and what states are deemed to be the most regulatory friendly for dronabinol.
GLAH
