KZA Media Thread, page-1864

Abstracts with Paxalisib are showing up. AACR had some tech problems earlier.

Apr 8 2022 12:00PM 5225. The PI3K inhibitor Paxalisib combines with the novel HDAC1/3 inhibitor RG2833 to improve survival in mice bearing orthotopic xenografts of atypical teratoid/rhabdoid tumors

Apr 8 2022 12:00PM 5226. The PI3K inhibitor Paxalisib combines synergistically with the pan-Raf inhibitor TAK580 (DAY 101) to extend survival in orthotopic xenograft models of atypical teratoid/rhabdoid tumors

Apr 13 2022 9:00AM 3987. Brain penetrant HDAC and PI3K/mTOR inhibitors synergize to induce DIPG cell death