Ann: Quarterly Activities Report and Appendix 4C, page-49

Just on Exopharm's commentary around loading of mRNA into exosomes via LOAD, it's also an exciting preliminary development. The potential for mRNA is huge ... mRNA-based vaccines for Covid is just the start!

This Spotify podcast, "Are We on Our Way to a Game-Changing Flu Vaccine?", explores the potential for mRNA therapeutics with Dr Schoenbeck - a Senior Vice President at Pfizer. Listen from 25:20 onwards for the commentary on mRNA's future. Schoenbeck highlights mRNA as a "new therapeutic modality", but for therapeutics beyond flu vaccines, a stronger delivery system is required. This is where exosomes may come into play!

Certainly interesting times ahead - particularly with most giant pharmas pursuing mRNA therapeutics.

https://open.spotify.com/episode/0LJGMXzEUsF87l2Pn9DW66?si=vcYJvQ5XRLKO-R-TRc-seg

There's also a great HBS article on the business and social implications of mRNA -

In the months and years ahead, mRNA platform owners such as Moderna and Pfizer and BioNTech will decide to what degree to open up their platforms to external parties and become orchestrators of an innovation ecosystem. They will have to weigh the benefits and drawbacks of allowing broad access or not.

https://hbr.org/2022/04/will-mrna-technology-companies-spawn-innovation-ecosystems?fbclid=IwAR0LiBoA1GKqoHLTGsBz-5C3uUpa3-WXP8x5-UTB7MqaUox7-yCuagJAJag