Absolutely phenomenal data! I've read this a bunch of times so that it really sinks in, and it's just so solid.
This result is achieved in the most aggressive, unresponsive mouse model with the greatest transferability to humans. The cancer is allowed to grow and thrive before treatment starts, which reflects what happens in humans.
It's really no surprise to me that Zan synergises with PD1 inhibitors, and that functioning as an FTO inhibitor influenes multiple systems related to immune system function. The dose response is particularly interesting for me.
Gee, I wonder what synergy with multiple commercial PD1 inhibitors would mean for potential partnership opportunities.
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