Kiwinvestor, there have been at least a couple, the most prominent in my mind is the donkey study. There was one also performed on MPS rats which was pretty amazing.
These excerpts from the Donkey study duly referenced below for your reading pleasure:
"This study confirms the previous reports on repair of articular
cartilage in the horses. Among these studies, it is generally accepted
that articular cartilage has limited reparative powers".
"These data clearly demonstrate the ability of PPS to stimulate the
biosynthesis of components of the extracellular matrix accompanied by
limiting their degradation by its anticatabolic effects".
https://irp-cdn.multiscreensite.com/d048e3f1/files/uploaded/JT%20-%20Pentosan-polysulfate-as-a-disease-modifier.pdf
Ann: Investor Presentation - $66m Capital Raise, page-76
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