looking good, page-13

thanks mr

in english, i think that means they have found some more very nice integrase inhibitors, that tibotec are about to get their hands on...

"The present inventors have now determined that a sub-class of these compounds are surprisingly effective (when compared to other members of the class) against viral variants containing the Q148H/G140S double mutation in integrase and the N155H/E92Q double mutation in integrase. This sub-class of compounds also shows surprising activity against the triple mutant Q148K/G140A/E138A."

I do like the reference to "surprising"...