Hi Matt
I would say that 847 is excellent too. The conclusion statement is less dramatic, but the result statement should be headline news: "CYCART-19 T cells induced potent cytolytic activity against solid tumor cells infected with onCARlytics."
They were trialling it in human liver cancer - xenografted into (I assume) mice. And they saw a "potent" effect of their CAR-T in that solid tumour. That really is outstanding!
Apparently they also tried a more traditional CAR-T product "PBMC-derived CD19-CAR T cells." That would be a CAR-T derived from Human peripheral blood mononuclear cells (PBMCs). That trial showed "comparable anti-tumour activity" - ie when used against solid tumor cells infected with onCARlytics.
So OnCARlytics works really well with both.
The difference - they point out - is that their placenta derived CYCART-19 drug had a much lower CRS (Cytokine Release Syndrome) side effect. CRS (a massive inflammatory response) is the most common toxicity related to CAR-T treatment and can be fatal.
So they are saying that their results validate OnCARlytics, but also validate CYCART-19 as a superior form of CAR-T because (when used in combo with OnCARlytics) it has a similar "potent" effectiveness to the more standard CAR-T but with less toxicity.
That could be a huge winning combination for Celularity and for Imugene....
I am amazed there is still no ASX Announcement. 3 preclinical studies validating OnCARlytics as effective for CAR-T in solid tumours - preclinical, of course. Fabulous news.
Cheers
Dave
- Forums
- ASX - By Stock
- IMU
- Media Thread
Media Thread, page-7357
-
- There are more pages in this discussion • 8,378 more messages in this thread...
You’re viewing a single post only. To view the entire thread just sign in or Join Now (FREE)
Featured News
NEWS
Antler Copper Project hits major permitting milestone – air quality permit advances to final review
CC9
Chariot Corporation (ASX:CC9) refines Black Mountain strategy, launching Pilot Mine to seize U.S. lithium opportunity
Add IMU (ASX) to my watchlist
(20min delay)
|
|||||
Last
4.8¢ |
Change
0.000(0.00%) |
Mkt cap ! $356.9M |
Open | High | Low | Value | Volume |
4.9¢ | 4.9¢ | 4.8¢ | $328.5K | 6.792M |
Buyers (Bids)
No. | Vol. | Price($) |
---|---|---|
45 | 5443565 | 4.8¢ |
Sellers (Offers)
Price($) | Vol. | No. |
---|---|---|
4.9¢ | 2171910 | 5 |
View Market Depth
No. | Vol. | Price($) |
---|---|---|
36 | 4613688 | 0.048 |
36 | 4066646 | 0.047 |
46 | 3070983 | 0.046 |
60 | 6170008 | 0.045 |
11 | 1951364 | 0.044 |
Price($) | Vol. | No. |
---|---|---|
0.049 | 1200533 | 2 |
0.050 | 4130537 | 15 |
0.051 | 6179811 | 13 |
0.052 | 2579418 | 10 |
0.053 | 1158504 | 8 |
Last trade - 16.10pm 04/10/2024 (20 minute delay) ? |
Featured News
IMU (ASX) Chart |