Ann: Paradigm AGM Presentation, page-85

You would lock in an upfront payment now (with further kickers, as they meet milestones, 008 data confirming DMOAD, FDA approval etc) because you need the money to get this across the finish line.... You haven't given away the farm, you have just ensured your survival to get through all the OA trials and not have to go back to the market place to do cap raisings...
We now know that a big pharma company, that was embroiled in the opioid fiasco, has put something forward, but it was rejected... In my view that is massive news and should have been used (still could be) to create some positive tension around someone (BP) trying to lock themselves into what looks like a truly remarkable molecule....

Look, it is obvious that they are still learning as they go along, as evidenced by the fact that they told us (only now) that 50% of MPS patients are treated with bone marrow transplants and there is no way anyone would partner with them until they knew how Zilosul worked with that cohort..