I read that Rhett suffers typically are on laxatives for constipation, and should Trof be prescribed that adjustments would need to be made if Trof is prescribed.
https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=&cad=rja&uact=8&ved=2ahUKEwiurreWk538AhU8zjgGHRINAn8QFnoECB8QAQ&url=https%3A%2F%2Fwww.neurologylive.com%2Fview%2Ftrofinetide-as-an-option-rett-syndrome-treatment&usg=AOvVaw0NLCrU4PyNDhpGG7UHflGW
Also this on touches on Acadia having a strategy in relation to the side effect of diarrhoea and also refers to how the FDA may call review panel if questions around side effects...perhaps Acadias strategy lodged with file for approval was sufficient and FDA didn't need review panel?
https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=&cad=rja&uact=8&ved=2ahUKEwjgj8m-kp38AhXJ2DgGHdpYBxIQFnoECBMQAQ&url=https%3A%2F%2Fwww.biopharmadive.com%2Fnews%2Facadia-rett-syndrome-phase-3-study-results%2F611091%2F&usg=AOvVaw3Rrydt_Qbo_7kH9R1tSqrm
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