Ann: Change of Director's Interest Notice, page-10

Is anyone aware of any other ASX company that has the Top 100 shareholders updated each month on Hot Copper?

Many thanks to RAN58 for his effort in making this publicly available..We must be one of the most transparent companies on the Bourse.

As others have stated, we are taking deliberate steps towards the main objectives. The strategies are fairly easy to understand. Long term holders are familiar with the scientific outline of MPL's mechanism of action on the mTOR pathway and are prepared to stay the course for a maximum outcome. Many in the Top 100 have been topping up at these bargain basement share prices. It is hardly unexpected that a Director would do the same when the opportunity arises. I'm top 50 and wishing I had ready cash to buy up more.

The major remaining question is "can the tablets actually validate the science?". Safety and tolerability is the first step along the road. A deep dive into the pharmacokinetics and optimum dosage levels will reveal more. Taking a tablet which may improve quality of life is far preferable to most other existing treatments. What we have learnt from the canine trial will provide a form-guide as to how MPL will behave in humans.

It has been a slow process up to this point but in my opinion there will come a time when sub-10 cents will be a long distance in the rear view mirror.