i was checking out the authors. They seem to be experts in the field.
https://www.researchgate.net/profile/Margaret-Smith-36https://sciprofiles.com/user/publications/2288748https://scholar.google.com/citations?user=fzBb8KEAAAAJ&hl=enJ.M. (James Melrose) has received consultancy fees from Arthropharm Pharmaceuticals Pty Ltd. M.M.S (Margaret M Smith). is a clinical research director at Arthropharm Pharmaceuticals Pty Ltd.
But tThey are associated wit Arthropharm Pty Ltd. This company bottles Cartrophen and Elmiron. in Australia and the have a Canadian arm.
https://www.arthropharm.com.au/abouthttps://www.tga.gov.au/resources/artg/48446https://apvma.gov.au/node/12326#AArthropharm Pty LtdAddress:105–113 Bronte RoadBondi Junction NSW 2022Licence No: 1107Product types:Category 1: Sterile products for injectionStep(s) of manufacture:Quality Assurance (QA) of raw materials, formulation including blending, aseptic filling, packaging, secondary packaging, labelling, sterilisation (heat, filtration), analysis and testing (physical, chemical, endotoxin, microbiological and sterility), storage and release for supply.Date of issue:24/10/2017
According to their website they are:
"Pioneers in the scientific research and clinical application of the large complex molecule PPS
Arthropharm Australia is a world leader in the research and development of sulfated polysaccharides"
They want people to contact them about Clinical trials for treatment of human arthritis
https://www.arthropharm.com.au/researchThe TGA gave them a slap on the wrist for "failure to provide information on a contact person responsible for medicine safety"
https://www.tga.gov.au/news/media-releases/arthropharm-pty-ltd-fined-13320-alleged-breaches-therapeutic-goods-legislationArthropharm seems to be a wholesale distributor.
So why are their associated scientists writing papers on PPS? and the website is talking about clinical trials?They have some patents as well...
https://goodip.io/iq/assignee/arthropharm-pty-ltdArthropharm own the patent for mammalian treatment:
https://patents.google.com/patent/US6593310B1/enPaul Rennie and Ravi Krishnan's abandonded patent references the Arthopharm patent
https://patents.google.com/patent/AU2018309566A1/koPeter Ghosh is on this one
https://patents.google.com/patent/US5145841A/en?assignee=Arthropharm+Pty+Ltd&oq=Arthropharm+Pty+LtdIt looks like the genesis of paradigm came from Arthropharm. I wonder if there are any competing claims possible down the track.
(20min delay)