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""Feature Articles: Jul 1 2010 (Vol. 30, No. 13)

Biomagnetic Separations' Abilities Increase
Gail Dutton Major Product Expansions Are Surfacing to Support an Assortment of Applications



Polysciences Bangs Labs division recently introduced the ProMag Bind-IT and 1 m ProMag microspheres. According to Kathy Turner, technical service manager, ProMag Bind-IT are 3 m polymer-based magnetic microspheres with a preactivated surface that allows ready binding of antibody without sacrificing stability. The beads and proteins bind during a simple incubation, and Bind-ITs chemistry immobilizes the antibody while preserving its tertiary structure for optimal activity.

Turner says a new size of ProMag magnetic microspheres is also available. Both the carboxyl and streptavidin versions are now available in a 1 m size. The smaller 1 m size offers far greater surface area per unit weight, which can present a considerable advantage for the purification of biomolecules or capture of low-concentration targets. Smaller-diameter spheres additionally remain suspended for longer periods of time, simplifying assay incubation steps.


http://www.genengnews.com/gen-articles/biomagnetic-separations-abilities-increase/3354/?page=3