For anyone interested there is a good video from the inventor of AOH1996 from May 23 here
https://ecancer.org/en/video/11266-aoh1996-treatment-targeting-pcna-shows-promise-for-reoccurring-solid-tumours
it seems to be making its way through the dose escalation without issue which is great. For some reason it’s a very small trial (8 patients only). It seems to have made a lot of headlines although the ‘successful results’ all seem to be preclinical at the moment. I hope it succeeds but suggest it’s pretty early days.
City of Hope cancer treatment, page-18
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