Good point re ambulant boys.
Good news is, ANP have identified the bio marker ATL1102 targets. They have also data showing the drug effective against this biomarker, including DMD. They have shown to that in combination with drugs addressing ambulant boys ATL1102 improves efficacy. We also have pre clinical data, from that same combo study showing ATL1102 worked well as a mono therapy. So rolling into ambulant boys, considering the good safety record at the moment should not present any problem. Particularly as the FDA does like biomarker data.
Non ambulant boys is a forgotten part of the DMD market. This helps with an accelerated pathway to approval.
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