RCE 2.86% 51.0¢ recce pharmaceuticals ltd

Acurx Pharmaceuticals, page-24

  1. 30 Posts.
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    Not really relevant to Clostridiodes difficile diarrhoea/colitis. It is the most common cause of in hospital diarrhoea and it is the toxin that causes the problem and can close whole hospital wards. The usual sequence of antibiotics is Metronidazole then vancomycin and a few others but this is a niche application although it is only oral rather than IV. This is not where the big bucks are so no competition from Recce.

    The thing that worried me about Recce (from a medical specialist point of view) is that the doses used are huge. They have trialed up to 16g IV in humans. But even very well studied Benzyl Penicillin for serious illnesses indication (endocarditis) goes only to 12g/d. Penicillin relatively resistant meningitis doses may go up to 20g. And these aren't really meant for 15 min infusions.
    I didn't buy Recce shares until the early toxicities were in showing no liver/kidney/CNS or other toxicities but they have been very well tolerated so far.

 
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