Alzheimer's and Monepantel, page-16

Hi Deebo,


Ferulic acid has iron chelating properties for a possible treatment of Multiple Systems Atrophy and Parkinson's.

Ferulic acid can affect neurones affected by iron bound to the neurones. The problem seems to be ferroptsis, rust on the neurones as opposed to plaque ( MND) on the neurones. The mTOR inhibitors don't work on " rust" removal , it's on a different lysosomes pathway. I do remember researching it a year or two ago.

Ferulic acid also needs nanoparticle technology to aid it in crossing the blood brain barrier though.

That other Company mentioned has a phase two on its compound ATH434 , of which it has achieved an ODD as well. The condition treated is MSA. They have done it hard over the last 7 years I have been invested in. Multiple Systems Atrophy is like MND with chips and salad. Extremely hard to treat. But, they are progressing with it like ourselves, and awaiting
trial data as well.

Kpax