The Final Charge , Phase I/II MND Results & FDA ODD Approval Catalyst, page-348

"............ The only thing that would make it better. . . is a patient symptom reversal. ..............."

Howdy Gpmm - suggest that would not be just better but bordering on a miracle. by the time you are diagnosed it is most likely there is already damage that simply cannot be reversed (see right side of image). Very poor analogy but if you burn a bunch of sticks they are gone. Real trick would be to prevent the onset in the first place and that may one day be a possibility but in the meantime early diagnosis and (hopefully) effective treatment will bring stability of disease. Having said that, the brain is an amazing thing. Maybe just perhaps some people will experience the upside of brain plasticity and regain to at least some extent some of the partially muted body functions. Only time will tell.
Meantime a (effective) treatment with little to notolerability issues, that enables extended quality of life, has to be a great thing.



Also noted a couple of comments re speed tickets. Personally would be more than disappointed on a couple of fronts if this were to prove correct. PAA has been stalled well below any reasonable MC. The last couple of weeks has seen plenty of reasonable indications by management leading to positive outcomes so that all we have seen so far is a sensible re-rating to base camp of the MC. By pretty much any benchmark suggest the SP could still double and not be overbought. Obviously nothing goes up in a straight line so there is bound to be a pause or correction at some stage however if one takes the time to look at what has been slated to be accomplished by the trial kick off date of Jun/July (see latest preso) there will be plenty of news to support the ongoing trading. Find me another baby bio at the recent MC that is sitting on :
1. Remarkable tolerability outcomes in both human and animal trials
2. Already having GMP grade full batch tablets
3. Clear potential to become a SOC for a clearly defined target with real possibility to follow on to a significant number of other ailments.
4. Advanced applications for trialing
5 Potentially only 24 months trialing required prior to approval
6. what every else I left out.
No disrespect intended to anyone however I personally have come to the conclusion that for we longer term holders it really is required to dump the memory of a lot of the history attached and look at this as a fresh investment starting around 6 months ago. The clear focus of messaging targeting the main prize is to be commended. Personally would like to have seen the liquid version kept under wraps for now however understand this has real value in sending a signal regards extended IP protection.

Wishing one and all a great weekend - next weeks news will come soon enough so dont wish your life away wanting the answers now. GLTAH