@JB1975
"Why should two treatments versus one treatment of the active (or hoped to be active agent) be a better test than the active agent alone (plus standard of care) versus null?"
A lot of 'old man yells at cloud' going on in your post. But on this specific point:
WHO THE funk IS GOING TO SIGN UP TO A TRIAL WHERE THEY GET NOTHING?
Ann: Appendix 3Y-Dr Geoffrey Brooke, page-4
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