Thanks Gino !
ABSTRACTS & PRESENTATIONS2024 ASCO Gastrointestinal Cancers Symposium - Poster SessionOncolytic virus CF33-hNIS monotherapy for the treatment of gastrointestinal (GI) malignancies.
CF33-hNIS is a novel chimeric DNA vaccinia virus engineered with the human sodium-iodide symporter (hNIS) gene. CF33-hNIS selectively replicates in tumor cells leading to cell lysis and the release of tumor- and virus-associated antigens stimulating antitumor immunity. Here, we report results of patients with GI malignancies enrolled on a first-in-human phase 1 ascending, multiple dose, safety and tolerability study of CF33-hNIS, administered intratumorally (IT) or intravenously (IV) in adult patients with metastatic or advanced solid tumors (MAST).
Abstract: 749 | Poster Bd #: M4
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