Pillar 1 - FTO (new thread), page-2917

Fantastic work Mason! I can’t believe you missed the all time GOAT of drug rediscovery - Viagra.

Sildenaf1l compound UK-92,480) was synthesized by a group of pharmaceutical chemists led by Simon Campbell^[54] working at Pfizer's Sandwich, Kent, research facility in England. It was initially studied for use in hypertension (high blood pressure) and angina pectoris (a symptom of ischaemic heart disease).^[55] The first clinical trials were conducted in Morriston Hospital in Swansea.^[56] Phase I clinical trials under the direction of Ian Osterloh suggested the drug had little effect on angina, but it could induce marked penile erections.^[57][58]Pfizer therefore decided to market it for erectile dysfunction, rather than for angina; this decision became an often-cited example of drug repositioning.^[59][60] The drug was patented in 1996, approved for use in erectile dysfunction by the FDA on 27 March 1998, becoming the first oral treatment approved to treat erectile dysfunction in the United States, and offered for sale in the United States later that year.^[61] It soon became a great success: annual sales of Viagra peaked in 2008 at US$1.934 billion.^[62]

https://en.wikipedia.org/wiki/*word disallowed by google

Edit. Interestingly you can’t post the word for the generic name of Viagra here on HC.