Carbonic anhydrase IX (CAIX) expression is found in a variety of cancers beyond clear cell renal cell carcinoma (ccRCC).
Here's a breakdown of some well-studied examples: Cancers with High CAIX Expression: Breast Cancer: Particularly aggressive subtypes like triple-negative breast cancer (TNBC) often show high CAIX levels.Head and Neck Squamous Cell Carcinoma (HNSCC): Studies indicate a link between high CAIX expression and poor prognosis in HNSCC.Glioblastoma: This aggressive brain tumor frequently expresses CAIX.Lung Cancer: Non-small cell lung cancer (NSCLC) can exhibit CAIX expression.Cervical Squamous Cell Carcinoma: This type of cervical cancer can show elevated CAIX levels.
I was researching using AI for potential targets for Zircaix (TLX250-CDx) or variants ,should it be successful ..quite surprised by the possibilities ...a great potential pipeline
Understanding Telix, page-1183
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