Cardioprotection thread, page-871

4/15 (26%) of patients at Sheba 2.0 experienced elevated Troponin levels.

Even a slight increase in the troponin level will often mean there has been some damage to the heart.

24-27% of Clofarabine patients experience cardiotoxicity (LV dysfunction) - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8352330/



If you were to sit in a quiet room and apply logic and deep thinking to the above; one might conclude that the cardiotoxic effect of Clofarabine was experienced by 26% of patients at Sheba 2.0. Fortunately, Clofarabine was also dosed with a drug that, albeit preclinically, has been shown to protect heart cells from damage by multiple anticancer agents...