OPT 1.83% 80.5¢ opthea limited

Opthea Q&A Sep 2024 Update, page-25

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    Year/MonthEvent/Activity
    11984Company Founded - Opthea was originally established as Circadian Technologies Limited.
    22015Company Rebranding - Opthea shifted its focus primarily to developing treatments for retinal diseases such as Wet AMD.
    32018-2020Phase 1/2a Trials (Sozinibercept) - Early clinical trials began to assess safety and efficacy in combination with anti-VEGF therapies.
    42021-2022Phase 2b Trials - Enrolled 366 Wet AMD patients. Top-line data: +5.7 letter improvement in BCVA at 24 weeks.
    5September 2023Capital Raising - Issued 160 million shares to institutional investors and 16 million shares to retail investors, raising A$82 million.
    6December 2023Amended DFA with Carlyle/Abingworth - Provided US$170 million in non-equity funding.
    7February 2024Phase 3 COAST Trial Enrollment Complete - 998 patients enrolled.
    8May 2024Phase 3 SHORE Trial Enrollment Complete - 986 patients enrolled.
    9June 2024Capital Raising - Issued shares to raise A$171.5 million, with an additional retail component raising A$55.9 million.
    10April 2025Top-line Data (COAST Trial) - Expected release of 52-week safety and efficacy results.
    11July-August 2025Top-line Data (SHORE Trial) - Expected release of 52-week safety and efficacy results.
    12September 2025OPTOA Options Expiry - OPTOA options (A$0.80 exercise price) expire.
    13April 202612-Month Safety Review (COAST Trial) - Long-term safety review of COAST trial.
    14June 2026OPTOB Options Expiry - OPTOB options (A$1.00 exercise price) expire.
    15July-August 202612-Month Safety Review (SHORE Trial) - Long-term safety review of SHORE trial.
    16Mid to Late 2026FDA Approval (Potential) - Sozinibercept could be approved for U.S. market entry.
    17Mid to Late 2026Capital Raising (for Commercialization) - Expected capital raise to fund commercialization.
    18Late 2026 - Early 2027Commercialization (Sozinibercept) - Sozinibercept could enter the U.S. market following FDA approval.



    Thanks, Pigrace! While I did build a knowledge base using GPT with public info on Opthea, the validation were done by me so got the date wrong.I've now improved the wording and included the long-term safety review, which happens 12 months after the topline results. I’ve also updated the SHORE topline readout timeline to allow an extra month for data analysis.Are there any other key dates that are wrong or missing?

 
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