ado research, major re rate on the way, page-4

Thanks mjc for posting that new info. appreciated. this is a long post but for holders and potential holders do read this. ive got some more new info here.

$179 for 2ml. i'm still trying to read into how much volume is required for each test, reading up some technical stuff to see i can properly quantify this 2ml amount.

so far from the promag bindit factsheet:
procedure is to dispense 100?L microsphere suspension. so 2ml = 2000?L so prolly 20 usages???

http://www.bangslabs.com/files/bangs/docs/pdf/PDS_735.pdf



from pg 19 of the AGM presentation:
the table mentioned about detection values in terms of per ml.
"Limit of detection values in pg/ml, except TSH (?IU/ml)"

would appreciate if someone with more technical knowledge speak about this aspect if possible, thanks.

i'm assuming that its the former that makes more sense, cos i know that some of the elisa type immunodignostics snap tests that i use in veterinary medicine (for heartworm etc) cost price is round about $20. it will make better sense if e sort of products that makes up the snap test is round about $9 (179/20 usages, as mentioned earlier).

i know that the royalties from the bang's agreement is a double figure %. so every unit of 2ml sold, >$18 bucks goes to ADO?? for easier calculations lets put it as $20. so assuming each 2ml product can be used for 20 tests.

ADO will profit $1 everytime a dignostic test (with ADO technology )is used???? <--- someone with more tech expertise pls do help. thanks.

(i also did abit of digging on Bang's lab, on ann, ADO mentioned Bangs being a big player in bead manufacturing. and i remembered that someone mentioned about the revenue size of bang's to be small 2.5-5mil pa. only today did i realise that this info that he shared months ago was not correct as it is outdated.

on bang's website it states that the coy is est 1988 apr. on the website (http://www.manta.com/c/mm87ps3/bangs-laboratories-inc) it showed that bangs is in biz for 7 years. so the info presented is outdated for 15years. couldnt dig anything out about bangs lab revenue which is more recent thou. so that 2.5-5mil pa is not reflective of bangs size today.

i'm not sure if u guys are following, i hope u do.


will write about the general info about immunodiagnostics with ADO. interesting notes from articles off ivdtech


what are microspheres??

Microspheres, beads, lattices are used in immunoassays to immobilize antibodies or antigens. Uses include procedures that involve washing steps and lateral-flow immunoassays in which antigen from a sample is bound to the antibody on the bead. That bead can carry the antigen-antibody complex to a colored bead that reacts to form a dot, line, or cross to indicate the presence of the antigen. Immunoassay devices use many variations of this use of beads.


how ADO's technology Mix&Go fit in??

In recent years microspheres have played an ever-increasing role as reaction surfaces for analyte testing. These substrates come in a wide variety of designs, each with features specific to their intended application.

Such features include specialty surface chemistry modification (linkers for antibody or antigen binding), labels and dyes in or on the microspheres (for detection purposes), and a wide range of sizes. This area of biotechnology will continue to grow as methods are optimized for the inclusion of microspheres into many test platforms used in reference laboratories or at the point of care.

ADO is involved in the surface chemistry modification. the increased surface binding of the antibodies to the microspheres and hence to the antigen allows smaller amounts of anaylate (ie blood, etc) to be detected. Thus disease are detected earlier and more treatment options are available for the patient.


Mix&go applicability to home-use platform, so what's home-use platform???

In recent years, there have been significant advances in home-use devices intended to permit closer monitoring of disease and enable patients to play a greater role in managing their own health. Already approved for use in monitoring patient levels of cholesterol, glucose, and oral anticoagulants, such platforms are now also gaining FDA approval for home testing of markers for certain cancers.


following tots are imo and from articles off www.ivdtechnology.com